thiol-activated haemolysins

thiol-activated haemolysins
(= oxygen-labile haemolysins)
Cytolytic bacterial exotoxins that act by binding to cholesterol in cell membranes and forming ring-like complexes that act as pores. SH-groups of these toxins must be in the reduced state for the toxin to function. Oxidation (to disulphide bridges) inactivates the toxin. Examples: tetanolysin, streptolysin O, q -toxin (perfringolysin), cereolysin.

Dictionary of molecular biology. 2004.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • perfringolysin O — (= theta toxin; q toxin) Cholesterol binding toxin from Clostridium perfringens. Shares with other thiol activated haemolysins a highly conserved sequence (ECTGLAWEWWR) near the C terminus …   Dictionary of molecular biology

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”